File:ALS_Disease_Pathology_and_Proposed_Disease_Mechanisms.jpg
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Summary
DescriptionALS Disease Pathology and Proposed Disease Mechanisms.jpg |
English: This figure is from the journal article "Modelling amyotrophic lateral sclerosis: progress and possibilities" and shows ten proposed disease mechanisms for ALS.
Fig. 1. ALS disease pathology and proposed disease mechanisms. At the level of cell pathology, ALS is characterized by axonal retraction and cell body loss of upper and lower motor neurons, surrounded by astrogliosis and microgliosis (see Box 2), with ubiquitin- and p62-positive inclusions in surviving neurons. Proposed disease mechanisms contributing to motor neuron degeneration are:
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Date | |
Source |
http://dmm.biologists.org/content/10/5/537
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Author | Philip Van Damme, Wim Robberecht, and Ludo Van Den Bosch |
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01:47, 9 January 2019 | 1,071 × 1,327 (1.21 MB) | AmericanLemming | uploading a new version of this file with less empty white space around the edges | ||
05:01, 30 December 2018 | 1,275 × 1,650 (1.17 MB) | AmericanLemming | User created page with UploadWizard |
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