User:Mr. Ibrahem/Dimenhydrinate
From Wikipedia, the free encyclopedia
Dimenhydrinate, marketed as Dramamine and Gravol among others, is a medication used to treat motion sickness, nausea, and vertigo.[3] While it maybe useful for allergies it has not been studied for this condition.[3] It is a combination of diphenhydramine and 8-chlorotheophylline.[1][4]
Combination of | |
---|---|
Diphenhydramine | Antiemetic |
8-chlorotheophylline | Stimulant |
Clinical data | |
Pronunciation | dye" men hye' dri nate[1] |
Trade names | Draminate, Gravol, Dramamine, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a607046 |
Pregnancy category |
|
Routes of administration | By mouth, rectal, intravenous, intramuscular[3] |
Drug class | First generation antihistamine[1] |
Legal status | |
Legal status | |
NY (what is this?) (verify) |
Common side effects include sleepiness, blurry vision, dry mouth, headache, confusion, and dizziness.[3][1] Children may become hyperactive.[3] Other side effects may include urinary retention and glaucoma.[1] It has been taken by many pregnant women without any evidence of harm to the baby.[2] Low doses when breastfeeding appear safe.[2] Dimenhydrinate is a first generation antihistamine.[1] It works mostly via the effects of diphenhydramine which blocks acetylcholine.[3] The 8-chlorotheophylline is present to try to decrease the side effect of sleepiness.[1]
Dimenhydrinate has been used medically since at least 1947 after being developed by G. D. Searle & Company.[5][6] It is avaliable over-the-counter drug and as a generic medication.[3] In the United States 120 tablets of 50 mg strength can be purchased for less than 10 USD as of 2020.[7] It may be used recreationally for the high that large doses can cause.[8][9]