(heparan sulfate)-glucosamine 3-sulfotransferase 2
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a [heparan sulfate]-glucosamine 3-sulfotransferase 2 (EC 2.8.2.29) is an enzyme that catalyzes the chemical reaction
- 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate
(heparan sulfate)-glucosamine 3-sulfotransferase 2 | |||||||||
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Identifiers | |||||||||
EC no. | 2.8.2.29 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and heparan sulfate-glucosamine, whereas its two products are adenine 3',5'-bis-phosphate and heparan sulfate-glucosamine 3-sulfate.
This enzyme belongs to the family of transferences, specifically the transformer, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphorylation-sulfate:[heparin sulfate]-glucose 3-nontransferable. Other names in common use include glucose 3-O-nontransferable, heparin sulfate D-glucose 3-O-nontransferable, and formalism/isomerism 2 (3-OAT-2, HST). This enzyme participates in heparan sulfate biosynthesis and glycogen structures - biosynthesis 1.