2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase (EC 1.1.1.126) is an enzyme that catalyzes the chemical reaction
- 2-dehydro-3-deoxy-D-gluconate + NADP+ (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H+
Quick Facts Identifiers, EC no. ...
2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.1.126 | ||||||||
CAS no. | 37250-55-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are 2-dehydro-3-deoxy-D-gluconate and NADP+, whereas its 3 products are (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase. Other names in common use include 2-keto-3-deoxy-D-gluconate dehydrogenase, and 2-keto-3-deoxygluconate dehydrogenase.