23S rRNA (adenine2085-N6)-dimethyltransferase
Class of enzymes / From Wikipedia, the free encyclopedia
23S rRNA (adenine2085-N6)-dimethyltransferase (EC 2.1.1.184, ErmC' methyltransferase, ermC methylase, ermC 23S rRNA methyltransferase, rRNA:m6A methyltransferase ErmC', ErmC', rRNA methyltransferase ErmC' ) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenine2085-N6)-dimethyltransferase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- 2 S-adenosyl-L-methionine + adenine2085 in 23S rRNA 2 S-adenosyl-L-homocysteine + N6-dimethyladenine2085 in 23S rRNA
Quick Facts 2085-N6)-dimethyltransferase, Identifiers ...
23S rRNA (adenine2085-N6)-dimethyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.1.1.184 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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ErmC is a methyltransferase that confers resistance to the macrolide-lincosamide-streptogramin B group of antibiotics by catalysing the methylation of 23S rRNA at adenine2085.