24,25-Dihydroxycholecalciferol
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24,25-Dihydroxycholecalciferol, also known as 24,25-dihydroxyvitamin D3 and (24R)-hydroxycalcidiol (abbreviated as 24(R),25-(OH)2D3),[1] is a compound which is closely related to 1,25-dihydroxyvitamin D3, the active form of vitamin D3. Like vitamin D3 itself and calcifediol (25-hydroxyvitamin D3), it is inactive as a hormone both in vitro[2] and in vivo.[3] It was first identified in 1972 in the laboratory of Hector DeLuca and Michael F. Holick.[4]
Quick Facts Names, Identifiers ...
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IUPAC name
(6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol | |
Other names
24,25-dihydroxyvitamin D3 (24R)-hydroxycalcifediol (24R)-hydroxycalcidiol | |
Identifiers | |
3D model (JSmol) |
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ECHA InfoCard | 100.049.754 |
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Properties | |
C27H44O3 | |
Molar mass | 416.63 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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