3-Methylmethcathinone
Substituted cathinone designer drug / From Wikipedia, the free encyclopedia
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3-Methylmethcathinone, also known as 3-MMC and metaphedrone,[3] is a designer drug from the substituted cathinone family. 3-MMC is closely related in structure to the more commonly known illicit drug mephedrone (4-MMC), and is also illegal in most countries that have banned mephedrone due to 3-MMC being a structural isomer of 4-MMC. However, 3-MMC has still appeared on the recreational drug market as an alternative to mephedrone, and was first identified being sold in Sweden in 2012.[4] Unlike some synthetic cathinones, 3-MMC has been evaluated in at least one large mammal study.[1] 3-MMC is a monoamine transporter substrate that potently inhibits norepinephrine uptake and displays more pronounced dopaminergic vs. serotonergic activity.[5]
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Bioavailability | Oral: 5%-9%[1] |
Protein binding | Low[1] |
Elimination half-life | 50 minutes[1] |
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Formula | C11H15NO |
Molar mass | 177.247 g·mol−1 |
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Melting point | 193.2 °C (379.8 °F) ± 0.2°C (hydrochloride salt) |
Boiling point | 280.5 °C (536.9 °F) ± 23.0°C at 760 mm Hg |
Solubility in water | Sparingly soluble in PBS; slightly soluble in ethanol, dimethyl sulfoxide, and dimethyl formamide.[2] mg/mL (20 °C) |
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