3alpha-hydroxycholanate dehydrogenase
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a 3alpha-hydroxycholanate dehydrogenase (EC 1.1.1.52) is an enzyme that catalyzes the chemical reaction
- 3alpha-hydroxy-5beta-cholanate + NAD+ 3-oxo-5beta-cholanate + NADH + H+
Quick Facts 3-alpha-hydroxycholanate dehydrogenase, Identifiers ...
3-alpha-hydroxycholanate dehydrogenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.1.52 | ||||||||
CAS no. | 9028-57-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are 3alpha-hydroxy-5beta-cholanate and NAD+, whereas its 3 products are 3-oxo-5beta-cholanate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase. This enzyme is also called alpha-hydroxy-cholanate dehydrogenase.