4-hydroxymandelate oxidase
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a 4-hydroxymandelate oxidase (EC 1.1.3.19) is an enzyme that catalyzes the chemical reaction
- (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate + O2 4-hydroxybenzaldehyde + CO2 + H2O2
Quick Facts Identifiers, EC no. ...
4-hydroxymandelate oxidase | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.3.19 | ||||||||
CAS no. | 60976-30-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate and O2, whereas its 3 products are 4-hydroxybenzaldehyde, CO2, and H2O2.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase. This enzyme is also called L-4-hydroxymandelate oxidase (decarboxylating). It has 2 cofactors: FAD, and Manganese.