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Chemical compound From Wikipedia, the free encyclopedia
5α-Dihydrocorticosterone (5α-DHC, 5α-DHB), also known as 11β,21-dihydroxy-5α-pregnane-3,20-dione, is a naturally occurring, endogenous glucocorticoid steroid hormone and neurosteroid.[1][2][3] It is biosynthesized from corticosterone by the enzyme 5α-reductase.[4][5][6] DHC has central depressant effects and impairs long-term potentiation in animals.[7][8]
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IUPAC name
11β,21-Dihydroxy-5α-pregnane-3,20-dione | |
Systematic IUPAC name
(1S,3aS,3bS,5aS,9aS,9bS,10S,11aS)-10-Hydroxy-1-(hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one | |
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Properties | |
C21H32O4 | |
Molar mass | 348.47638 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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