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7α-Hydroxycholesterol

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7α-Hydroxycholesterol
Names
IUPAC name
(3S,7S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
Identifiers
3D model (JSmol)
ChemSpider
MeSH 7+alpha-hydroxycholesterol
UNII
Properties
C27H46O2
Molar mass 402.653 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

7α-Hydroxycholesterol is a precursor of bile acids, created by cholesterol 7α-hydroxylase. Its formation is the rate-determining step in bile acid synthesis.[1]

References

  1. ^ Miao J (2008). Regulation of Bile Acid Biosynthesis by Orphan Nuclear Receptor Small Heterodimer Partner (Ph.D.). University of Illinois at Urbana-Champaign.



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7α-Hydroxycholesterol
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