Alpha-tubulin N-acetyltransferase
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In enzymology, an alpha-tubulin N-acetyltransferase (EC 2.3.1.108) is an enzyme which is encoded by the ATAT1 gene.
Quick Facts Identifiers, EC no. ...
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This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:[alpha-tubulin]-L-lysine N6-acetyltransferase. Other names in common use include alpha-tubulin acetylase, αTAT, ATAT1, TAT, alpha-TAT, alpha-tubulin acetyltransferase, tubulin N-acetyltransferase, acetyl-CoA:alpha-tubulin-L-lysine N-acetyltransferase, and acetyl-CoA:[alpha-tubulin]-L-lysine 6-N-acetyltransferase.
More information Protein information, Value ...
Protein information | Value |
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Molecular mass | 46810 Da |
Size (Amino-acid size) | 421 amino acids |
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More information Kinetic indicators, Value ...
Kinetic indicators | Value |
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Km for free alpha-tubulin | 2.0 μM |
Km for polymerized tubulin | 1.6 μM |
Km for acetyl-CoA | 2.2 μM |
Kcat for the acetylation of polymerized tubulin | 2.2 h−1 |
Kcat for the acetylation of free tubulin | 0.35 h−1 |
Kcat with acetyl-CoA | 1.47 h−1 |
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