3α-Hydroxysteroid dehydrogenase
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about AKR1C4?
Summarize this article for a 10 year old
SHOW ALL QUESTIONS
3α-Hydroxysteroid dehydrogenase type 1 (3α-HSD1)[5][6][7] or aldo-keto reductase family 1 member C4 is an enzyme that in humans is encoded by the AKR1C4 gene.[8][9][10] It is known to be necessary for the synthesis of the endogenous neurosteroids allopregnanolone, THDOC, and 3α-androstanediol. It is also known to catalyze the reversible conversion of 3α-androstanediol (5α-androstane-3α,17β-diol) to dihydrotestosterone (DHT, 5α-androstan-17β-ol-3-one) and vice versa.[11]
A request that this article title be changed to AKR1C4 is under discussion. Please do not move this article until the discussion is closed. |
Quick Facts AKR1C4, Available structures ...
Close