Alanine dehydrogenase
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Alanine dehydrogenase (EC 1.4.1.1) is an enzyme that catalyzes the chemical reaction
- L-alanine + H2O + NAD+ pyruvate + NH3 + NADH + H+
Quick Facts Identifiers, EC no. ...
alanine dehydrogenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.4.1.1 | ||||||||
CAS no. | 9029-06-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The 2 substrates of this enzyme are L-alanine, water, and nicotinamide adenine dinucleotide+ because water is 55M and does not change, whereas its 4 products are pyruvate, ammonia, NADH, and hydrogen ion.
This enzyme participates in taurine and hypotaurine metabolism and reductive carboxylate cycle (CO2 fixation).