Azatadine
Chemical compound / From Wikipedia, the free encyclopedia
Azatadine (Optimine) is a first-generation antihistamine and anticholinergic drug that was synthesized in 1963 by Schering-Plough, a former American pharmaceutical company.[1][2]
Not to be confused with azetidine.
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Trade names | Optimine |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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Formula | C20H22N2 |
Molar mass | 290.410 g·mol−1 |
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It was patented in 1967.[3] It has been succeeded by both loratadine and desloratadine.[4]: 53 and marketing approvals have been widely withdrawn.[5][6][7][8]: 290 [9]
- US 3326924, Villani FJ, Caldwell W, "Azatadine", issued 1967
- Horak F (2010). "Antialergic and Vasoactive Drugs for Allergic Rhinitis. Chapter 4". In Pawankar R, Holgate ST, Rosenwasser LJ (eds.). Allergy Frontiers:Therapy and Prevention. Vol. 5. Springer Science & Business Media. ISBN 9784431993629.
- "Azatadine". Drugs.com.
- Food and Drug Administration (2005). "Docket No.2005N-0058: Hospira, Inc. et al.; Withdrawal of Approval of 76 New Drug Applications and 60 Abbreviated New Drug Applications". Federal Register 70 FR 10651.
- Food and Drug Administration (2007). "Docket No. 2004P-0262: Withdrawal of Approval of 128 Suitability Petitions". Federal Register 72 FR 8184.
- "Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals" (PDF). Department of Economic and Social Affairs of the United Nations Secretariat. New York: United Nations. 2005.
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