Butriptyline
Atypical tricyclic antidepressant medication / From Wikipedia, the free encyclopedia
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Butriptyline, sold under the brand name Evadyne among others, is a tricyclic antidepressant (TCA) that has been used in the United Kingdom and several other European countries for the treatment of depression but appears to no longer be marketed.[1][4][5][6][7] Along with trimipramine, iprindole, and amoxapine, it has been described as an "atypical" or "second-generation" TCA due to its relatively late introduction and atypical pharmacology.[8][9] It was very little-used compared to other TCAs, with the number of prescriptions dispensed only in the thousands.[10]
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Evadyne, others |
Other names | AY-62014[1] |
Routes of administration | Oral |
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Bioavailability | ?[3] |
Protein binding | >90%[3] |
Metabolism | Hepatic (N-demethylation) |
Metabolites | Norbutriptyline[3] |
Elimination half-life | 20 hours[3] |
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Chemical and physical data | |
Formula | C21H27N |
Molar mass | 293.454 g·mol−1 |
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Chirality | Racemic mixture |
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