Channelome
From Wikipedia, the free encyclopedia
The channelome, sometimes called the "ion channelome", is the complete set of ion channels[1] and porins[2] expressed in a biological tissue or organism.[3] It is analogous to the genome, the metabolome (describing metabolites), the proteome (describing general protein expression), and the microbiome. Characterization of the ion channelome, referred to as channelomics, is a branch of physiology, biophysics, neuroscience, and pharmacology, with particular attention paid to gene expression.[4][5][6] It can be performed by a variety of techniques, including patch clamp electrophysiology, PCR, and immunohistochemistry.[4][7] Channelomics is being used to screen and discover new medicines.[4][8]