Chitobiosyldiphosphodolichol beta-mannosyltransferase
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) is an enzyme that catalyzes the chemical reaction
- GDP-mannose + chitobiosyldiphosphodolichol GDP + beta-1,4-D-mannosylchitobiosyldiphosphodolichol
chitobiosyldiphosphodolichol beta-mannosyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.4.1.142 | ||||||||
CAS no. | 83380-85-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are GDP-mannose and chitobiosyldiphosphodolichol, whereas its two products are GDP and beta-1,4-D-mannosylchitobiosyldiphosphodolichol.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase. Other names in common use include guanosine diphosphomannose-dolichol diphosphochitobiose, mannosyltransferase, and GDP-mannose-dolichol diphosphochitobiose mannosyltransferase. This enzyme participates in n-glycan biosynthesis and glycan structures - biosynthesis 1.