David or Dave Murphy may refer to:
Sports
- David Murphy (Australian rules footballer) (born 1962), Australian rules footballer
- Dave Murphy (baseball) (1876–1940), American shortstop in Major League Baseball
- David Murphy (baseball) (born 1981), American baseball player
- David Murphy (cricketer) (born 1989), Scottish cricketer
- David Murphy (footballer, born 1917) (1917–1944), English footballer
- David Murphy (footballer, born 1984), English footballer
- David Murphy (Laois Gaelic footballer) (born 1985), Gaelic footballer
- David Murphy (Wexford Gaelic footballer), Gaelic footballer
Others
- David Murphy (CIA) (1921–2014), CIA station chief in Berlin, 1959–1961
- David Murphy (composer), Irish composer and harper
- David Lee Murphy (born 1959), American country music singer-songwriter
- David Murphy (Irish writer), Irish author
- Dave Murphy (Wisconsin politician) (born 1954), American businessman and politician
- David Murphy, contestant on Survivor: Redemption Island (2011)
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