Diaminopimelate dehydrogenase
From Wikipedia, the free encyclopedia
In enzymology, a diaminopimelate dehydrogenase (EC 1.4.1.16) is an enzyme that catalyzes the chemical reaction
- meso-2,6-diaminoheptanedioate + H2O + NADP+ L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+
Quick Facts Identifiers, EC no. ...
diaminopimelate dehydrogenase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 1.4.1.16 | ||||||||
CAS no. | 60894-21-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
Close
The 3 substrates of this enzyme are meso-2,6-diaminoheptanedioate, H2O, and NADP+, whereas its 4 products are L-2-amino-6-oxoheptanedioate, NH3, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating). Other names in common use include meso-alpha,epsilon-diaminopimelate dehydrogenase, and meso-diaminopimelate dehydrogenase. This enzyme participates in lysine biosynthesis.