Dicloxacillin
Chemical compound / From Wikipedia, the free encyclopedia
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Dicloxacillin is a narrow-spectrum β-lactam antibiotic of the penicillin class.[1] It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria.[1] It is active against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins. Dicloxacillin is available under a variety of trade names including Diclocil (BMS).[2]
Quick Facts Clinical data, AHFS/Drugs.com ...
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AHFS/Drugs.com | Monograph |
MedlinePlus | a685017 |
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Routes of administration | Oral |
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Bioavailability | 60 to 80% |
Protein binding | 98% |
Metabolism | Hepatic |
Elimination half-life | 0.7 hours |
Excretion | Renal and biliary |
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ECHA InfoCard | 100.019.535 |
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Formula | C19H17Cl2N3O5S |
Molar mass | 470.32 g·mol−1 |
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It was patented in 1961 and approved for medical use in 1968.[3] It is available as a generic medication.[4]