Dimenhydrinate
Anti-emetic and antihistamine medication / From Wikipedia, the free encyclopedia
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Not to be confused with diphenhydramine.
"Dramamine" redirects here. For other uses, see Dramamine (disambiguation).
Dimenhydrinate, sold under the brand name Dramamine, among others, is an over-the-counter medication used to treat motion sickness and nausea. Dimenhydrinate is a theoclate salt composed of diphenhydramine (an ethanolamine derivative) and 8-chlorotheophylline (a chlorinated theophylline derivative) in a 1:1 ratio.[2]
Quick Facts Combination of, Diphenhydramine ...
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Diphenhydramine | Antihistamine, sedative |
8-chlorotheophylline | Stimulant |
Clinical data | |
Trade names | Dramamine, Draminate, Gravol, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a607046 |
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Routes of administration | By mouth, rectal, intravascular, intramuscular |
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Metabolism | Liver |
Elimination half-life | 5.5 hours[1] (diphenhydramine component) |
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ECHA InfoCard | 100.007.593 |
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Dimenhydrinate was introduced to the market by G.D. Searle in 1949.[3][4]