Dimethylallyltranstransferase
Mammalian protein found in Homo sapiens / From Wikipedia, the free encyclopedia
Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an enzyme that in humans is encoded by the FDPS gene and catalyzes the transformation of dimethylallylpyrophosphate (DMAPP) and isopentenyl pyrophosphate (IPP) into farnesylpyrophosphate (FPP).[5][6]
Quick Facts FDPS, Available structures ...
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Quick Facts Identifiers, EC no. ...
Dimethylallyltranstransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.5.1.1 | ||||||||
CAS no. | 9032-79-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Quick Facts Farnesyldiphosphate synthase (farnesylpyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase), Identifiers ...
Farnesyldiphosphate synthase (farnesylpyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | |||||||
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Identifiers | |||||||
Symbol | FDPS | ||||||
NCBI gene | 2224 | ||||||
HGNC | 3631 | ||||||
OMIM | 134629 | ||||||
RefSeq | NM_002004 | ||||||
UniProt | P14324 | ||||||
Other data | |||||||
EC number | 2.5.1.1 | ||||||
Locus | Chr. 1 q22 | ||||||
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Pyrophosphate is also involved, as both a reactant and a product. Geranylpyrophosphate is created in an intermediate step.