EA-4056
Chemical compound / From Wikipedia, the free encyclopedia
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Quick Facts Names, Identifiers ...
Names | |
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IUPAC name
1,9-Bis[methyl-2(3-dimethylcarbamoxypyridyl)methylamino]nonane dimethobromide | |
Preferred IUPAC name
N1,N9-Bis({3-[(dimethylcarbamoyl)oxy]pyridin-2-yl}methyl)-N1,N1,N9,N9-tetramethylnonane-1,9-bis(aminium) dibromide | |
Identifiers | |
3D model (JSmol) |
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Properties | |
C31H52N6O4 · Br2 | |
Molar mass | 732.6 g/mol |
Appearance | crystalline solid |
Melting point | 100–105 °C |
Solubility | soluble in water and alcohols |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
11 µg/kg for mice and 2.7 µg/kg for rabbits via IV |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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EA-4056 is a deadly carbamate nerve agent. It is lethal because it inhibits acetylcholinesterase.[1] Inhibition causes an overly high accumulation of acetylcholine between the nerve and muscle cells. This paralyzes the muscles by preventing their relaxation. The paralyzed muscles includes the muscles used for breathing.[2]
Patent assigned to US Army for EA-4056 among other similar nerve agents was filed in December 7, 1967.[3]