In enzymology, a (R)-3-hydroxyacid-ester dehydrogenase (EC 1.1.1.279) is an enzyme that catalyzes the chemical reaction
- ethyl (R)-3-hydroxyhexanoate + NADP+ ethyl 3-oxohexanoate + NADPH + H+
| (R)-3-hydroxyacid-ester dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.279 | ||||||||
| CAS no. | 114705-02-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are ethyl (R)-3-hydroxyhexanoate and NADP+, whereas its 3 products are ethyl 3-oxohexanoate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase. This enzyme is also called 3-oxo ester (R)-reductase.
References
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