3-hydroxy-4-oxoquinoline 2,4-dioxygenase
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a 3-hydroxy-4-oxoquinoline 2,4-dioxygenase (EC 1.13.11.47) is an enzyme that catalyzes the chemical reaction
- 3-hydroxy-1H-quinolin-4-one + O2 N-formylanthranilate + CO
3-hydroxy-4-oxoquinoline 2,4-dioxygenase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 1.13.11.47 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
Thus, the two substrates of this enzyme are 3-hydroxy-1H-quinolin-4-one and O2, whereas its two products are N-formylanthranilate and CO.
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 3-hydroxy-1H-quinolin-4-one 2,4-dioxygenase (CO-forming). Other names in common use include (1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase, 3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase, 3-hydroxy-4(1H)-one, 2,4-dioxygenase, and quinoline-3,4-diol 2,4-dioxygenase.