From Wikipedia, the free encyclopedia
|AHFS/Drugs.com||International Drug Names|
|Chemical and physical data|
|Molar mass||3363.78 g/mol g·mol−1|
|3D model (JSmol)|
It is transformed from eel's calcitonin by changing the S-S bond into a stable C-N bond. It inhibits the absorption and autolysis of bones and thus leads to lowering of blood calcium. It inhibits bone salts from dissolving and transferring and promotes the excretion of calcium and phosphorus in the urine. It inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at a normal level. It is mainly used for remitting or eliminating pain caused by osteoporosis.
- Yoh, K.; Uzawa, T.; Orito, T.; Tanaka, K. (2012). "Improvement of Quality of Life (QOL) in Osteoporotic Patients by Elcatonin Treatment: A Trial Taking the Participants' Preference into Account". Japanese Clinical Medicine. 3: JCM.S8291. doi:10.4137/JCM.S8291. PMC 3738553.
- Tanaka, Shinya; Yoshida, Akira; Kono, Shinjiro; Oguma, Tadanori; Hasegawa, Kyoichi; Ito, Manabu (2017). "Effectiveness of elcatonin for alleviating pain and inhibiting bone resorption in patients with osteoporotic vertebral fractures". Journal of Bone and Mineral Metabolism. 35 (5): 544–553. doi:10.1007/s00774-016-0791-6. PMID 27830386.
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.