Frizzled-6
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Frizzled-6 (Fz-6) is a protein that in humans is encoded by the FZD6 gene.[5][6][7]
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Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for WNT signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 transmembrane domains. However, unlike many other FZD family members, FDZ6 does not contain a C-terminal PDZ domain-binding motif.[7] Fz-6 is believed to be the receptor for the WNT4 ligand.[8]