Fibrillin
Protein family / From Wikipedia, the free encyclopedia
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Not to be confused with Fibrin.
Fibrillin is a glycoprotein, which is essential for the formation of elastic fibers found in connective tissue.[2] Fibrillin is secreted into the extracellular matrix by fibroblasts and becomes incorporated into the insoluble microfibrils, which appear to provide a scaffold for deposition of elastin.[3]
Quick Facts Identifiers, Symbol ...
fibrillin 1 | |||||||
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Identifiers | |||||||
Symbol | FBN1 | ||||||
Alt. symbols | FBN, MFS1, WMS | ||||||
NCBI gene | 2200 | ||||||
HGNC | 3603 | ||||||
OMIM | 134797 | ||||||
PDB | 2W86 | ||||||
RefSeq | NM_000138 | ||||||
UniProt | P35555 | ||||||
Other data | |||||||
Locus | Chr. 15 q21.1 | ||||||
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Quick Facts Identifiers, Symbol ...
fibrillin 2 | |||||||
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Identifiers | |||||||
Symbol | FBN2 | ||||||
Alt. symbols | CCA | ||||||
NCBI gene | 2201 | ||||||
HGNC | 3604 | ||||||
OMIM | 121050 | ||||||
RefSeq | NM_001999 | ||||||
UniProt | P35556 | ||||||
Other data | |||||||
Locus | Chr. 5 q23-q31 | ||||||
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Quick Facts Identifiers, Symbol ...
fibrillin 3 | |||||||
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Identifiers | |||||||
Symbol | FBN3 | ||||||
NCBI gene | 84467 | ||||||
HGNC | 18794 | ||||||
OMIM | 608529 | ||||||
RefSeq | NM_032447 | ||||||
UniProt | Q75N90 | ||||||
Other data | |||||||
Locus | Chr. 19 p13 | ||||||
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