Gadolinium(III) hydroxide

Gadolinium(III) hydroxide is a chemical compound with the formula Gd(OH)₃. Its nanoparticles has a potential use for layering various drugs, such as diclofenac, ibuprofen, and naproxen.

Gadolinium(III) hydroxide

Names
Systematic IUPAC name Gandolinium trihydroxide
Other names Gandolinium(III) hydroxide
Identifiers
CAS Number	16469-18-4
3D model (JSmol)	Interactive image
ChemSpider	77048
ECHA InfoCard	100.036.817
EC Number	240-516-5
PubChem CID	85434
CompTox Dashboard (EPA)	DTXSID80936979
InChI InChI=1S/Gd.3H2O/h;3*1H2/q+3;;;/p-3 Key: ILCLBMDYDXDUJO-UHFFFAOYSA-K
SMILES [OH-].[OH-].[OH-].[Gd+3]
Properties
Chemical formula	Gd(OH)3
Molar mass	208.3 g/mol
Appearance	White solid
Melting point	307 °C (585 °F; 580 K)[1] (decomposes)
Solubility in water	Insoluble
Structure
Crystal structure	Hexagonal[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Production and properties

Gadolinium(III) hydroxide can be produced in various ways such as the reaction of gadolinium(III) nitrate and sodium hydroxide:^[1]

Gd(NO₃)₃ + NaOH → Gd(OH)₃ + NaNO₃

If this compound is heated to 307 °C, it decomposes to gadolinium(III) oxide-hydroxide(GdOOH), which in turn decomposes to gadolinium(III) oxide if continually heated.^[1]

Uses

Gadolinium(III) hydroxide has no commercial uses. However, gadolinium(III) hydroxide nanoparticles have gained interest as a coating agent for various anti-inflammatory drugs such as diclofenac, ibuprofen, and naproxen^[3] due to their property to be non-cytotoxic.^[4] The nanoparticles are produced by adding base anion exchange resin to gadolinium(III) nitrate.^[2]