Galactosylxylosylprotein 3-beta-galactosyltransferase
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a galactosylxylosylprotein 3-beta-galactosyltransferase (EC 2.4.1.134) is an enzyme that catalyzes the chemical reaction
- UDP-galactose + 4-beta-D-galactosyl-O-beta-D-xylosylprotein UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein
galactosylxylosylprotein 3-beta-galactosyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.4.1.134 | ||||||||
CAS no. | 56626-21-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are UDP-galactose and 4-beta-D-galactosyl-O-beta-D-xylosylprotein, whereas its two products are UDP and 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase. Other names in common use include galactosyltransferase II, and uridine diphosphogalactose-galactosylxylose galactosyltransferase. This enzyme participates in chondroitin sulfate biosynthesis and glycan structures - biosynthesis 1. It employs one cofactor, manganese.