Gentamicin 3'-N-acetyltransferase
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In enzymology, a gentamicin 3'-N-acetyltransferase (EC 2.3.1.60) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + gentamicin C CoA + N3'-acetylgentamicin C
Quick Facts Identifiers, EC no. ...
gentamicin 3'-N-acetyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.3.1.60 | ||||||||
CAS no. | 58500-58-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are acetyl-CoA and gentamicin C, whereas its two products are CoA and N3'-acetylgentamicin C.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:gentamicin-C N3'-acetyltransferase. Other names in common use include gentamicin acetyltransferase I, aminoglycoside acetyltransferase AAC(3)-1, gentamicin 3'-N-acetyltransferase, and acetyl-CoA:gentamicin-C N3'-acetyltransferase.