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From Wikipedia, the free encyclopedia
In enzymology, a glucuronate isomerase (EC 5.3.1.12) is an enzyme that catalyzes the chemical reaction
glucuronate isomerase | |||||||||
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Identifiers | |||||||||
EC no. | 5.3.1.12 | ||||||||
CAS no. | 9023-87-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Hence, this enzyme has one substrate, D-glucuronate, and one product, D-fructuronate.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-glucuronate aldose-ketose-isomerase. Other names in common use include uronic isomerase, uronate isomerase, D-glucuronate isomerase, uronic acid isomerase, and D-glucuronate ketol-isomerase. This enzyme participates in pentose and glucuronate interconversions.
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1J5S and 2Q01.
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