Glutamate formimidoyltransferase
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Glutamate formimidoyltransferase is a methyltransferase enzyme which uses tetrahydrofolate as part of histidine catabolism. It catalyses two reactions:
- 5-formimidoyltetrahydrofolate + L-glutamate <=> tetrahydrofolate + N-formimidoyl-L-glutamate
- 5-formyltetrahydrofolate + L-glutamate <=> tetrahydrofolate + N-formyl-L-glutamate
Quick Facts Formiminotransferase domain, N-terminal subdomain, Identifiers ...
Formiminotransferase domain, N-terminal subdomain | |||||||||
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Identifiers | |||||||||
Symbol | FTCD_N | ||||||||
Pfam | PF07837 | ||||||||
InterPro | IPR012886 | ||||||||
SCOP2 | 1qd1 / SCOPe / SUPFAM | ||||||||
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Quick Facts Formiminotransferase domain, Identifiers ...
Formiminotransferase domain | |||||||||
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Identifiers | |||||||||
Symbol | FTCD | ||||||||
Pfam | PF02971 | ||||||||
InterPro | IPR013802 | ||||||||
SCOP2 | 1qd1 / SCOPe / SUPFAM | ||||||||
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It is classified under EC 2.1.2.5 and in mammals is found as part of a bifunctional enzyme that also has formimidoyltetrahydrofolate cyclodeaminase activity.[1]