Group I catalytic intron
Large self-splicing ribozymes / From Wikipedia, the free encyclopedia
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Group I introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms.[1][2][3] The core secondary structure consists of nine paired regions (P1-P9).[4] These fold to essentially two domains – the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices).[2] The secondary structure mark-up for this family represents only this conserved core. Group I introns often have long open reading frames inserted in loop regions.