Holt–Oram syndrome
Medical condition / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Holt–Oram syndrome?
Summarize this article for a 10 year old
SHOW ALL QUESTIONS
Holt–Oram syndrome (also called atrio-digital syndrome, atriodigital dysplasia, cardiac-limb syndrome, heart-hand syndrome type 1, HOS, ventriculo-radial syndrome) is an autosomal dominant disorder that affects bones in the arms and hands (the upper limbs) and often causes heart problems.[1] The syndrome may include an absent radial bone in the forearm, an atrial septal defect in the heart, or heart block.[2] It affects approximately 1 in 100,000 people.[2]
Quick Facts Other names, Specialty ...
Holt-Oram syndrome | |
---|---|
Other names | Heart-hand syndrome, Atrio-digital syndrome, Atriodigital dysplasia |
Holt-Oram syndrome has an autosomal dominant pattern of inheritance | |
Specialty | Medical genetics |
Causes | Mutations in the TBX5 gene |
Close