Loading AI tools
From Wikipedia, the free encyclopedia
In enzymology, a hydroxymethylpyrimidine kinase (EC 2.7.1.49) is an enzyme that catalyzes the chemical reaction
hydroxymethylpyrimidine kinase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 2.7.1.49 | ||||||||
CAS no. | 9026-55-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
Thus, the two substrates of this enzyme are ATP and 4-amino-5-hydroxymethyl-2-methylpyrimidine, whereas its two products are ADP and 4-amino-5-phosphonooxymethyl-2-methylpyrimidine.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase. This enzyme is also called hydroxymethylpyrimidine kinase (phosphorylating). This enzyme participates in thiamine metabolism.
Seamless Wikipedia browsing. On steroids.
Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.
Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.