Hyoscyamine
Tropane alkaloid / From Wikipedia, the free encyclopedia
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Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, the sorcerers' tree, and Atropa belladonna (deadly nightshade). It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine.[1]
Quick Facts Clinical data, Trade names ...
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Trade names | Anaspaz, Levbid, Levsin |
AHFS/Drugs.com | Monograph |
MedlinePlus | a684010 |
Routes of administration | By mouth, Injection |
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Pharmacokinetic data | |
Bioavailability | 50% protein binding |
Metabolism | Liver |
Elimination half-life | 3–5 hrs. |
Excretion | Kidney |
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ECHA InfoCard | 100.002.667 |
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Formula | C17H23NO3 |
Molar mass | 289.375 g·mol−1 |
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In 2021, it was the 272nd most commonly prescribed medication in the United States, with more than 900,000 prescriptions.[2][3]