In enzymology, an indoleacetate—lysine synthetase (EC 6.3.2.20) is an enzyme that catalyzes the chemical reaction
- ATP + (indol-3-yl)acetate + L-lysine ADP + phosphate + N6-[(indol-3-yl)acetyl]-L-lysine
| Indoleacetate—lysine synthetase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 6.3.2.20 | ||||||||
| CAS no. | 103537-15-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The 3 substrates of this enzyme are ATP, (indol-3-yl)acetate, and L-lysine, whereas its 3 products are ADP, phosphate, and [[N6-[(indol-3-yl)acetyl]-L-lysine]].
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is (indol-3-yl)acetate:L-lysine ligase (ADP-forming). This enzyme is also called indoleacetate:L-lysine ligase (ADP-forming).
References
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