JNJ-5207852
Chemical compound / From Wikipedia, the free encyclopedia
JNJ-5207852 is a histamine antagonist selective for the H3 subtype. It has stimulant and nootropic effects in animal studies,[1] and has been suggested as a possible treatment for some memory defects associated with epilepsy.[2] JNJ-5207852 itself did not progress to clinical development due to poor pharmacokinetic characteristics, but the related compound JNJ-17216498 was in a Phase II clinical trial for the treatment of narcolepsy in 2007.[3]
Quick Facts Names, Identifiers ...
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Preferred IUPAC name
1-(3-{4-[(piperidin-1-yl)methyl]phenoxy}propyl)piperidine | |
Identifiers | |
3D model (JSmol) |
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Abbreviations | JNJ-5207852 |
ChEMBL | |
ChemSpider |
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MeSH | JNJ-5207852 |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C20H32N2O | |
Molar mass | 316.480 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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