Leukotriene receptor
Protein family / From Wikipedia, the free encyclopedia
The leukotriene (LT) receptors are G protein-coupled receptors that bind and are activated by the leukotrienes. They include the following proteins:
- Leukotriene B4 receptors (BLTRs) – bind to and are activated by LTB4:
- BLT1 (Leukotriene B4 receptor 1) – LTB4R
- BLT2 (Leukotriene B4 receptor 2) – LTB4R2
- Cysteinyl leukotriene receptors (CysLTRs) – bind to and are activated by LTC4, LTD4, and LTE4:
- CysLT1 (Cysteinyl leukotriene receptor 1) – CYSLTR1
- CysLT2 (Cysteinyl leukotriene receptor 2) – CYSLTR2
The recently elucidated CysLTE, represented by GPR99/OXGR1, may constitute a third CysLTR.[1]