Lorcainide
Antiarrythmic agent / From Wikipedia, the free encyclopedia
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Lorcainide (Lorcainide hydrochloride) is a Class 1c antiarrhythmic agent that is used to help restore normal heart rhythm and conduction in patients with premature ventricular contractions, ventricular tachycardiac[1] and Wolff–Parkinson–White syndrome.[2] Lorcainide was developed by Janssen Pharmaceutica (Belgium) in 1968 under the commercial name Remivox and is designated by code numbers R-15889 or Ro 13-1042/001.[3] It has a half-life of 8.9 +- 2.3 hrs which may be prolonged to 66 hrs in people with cardiac disease.[2]
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Protein binding | 78 |
Elimination half-life | 14.3 +/-3.7 |
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Formula | C22H27ClN2O |
Molar mass | 370.92 g·mol−1 |
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