Mismatch repair cancer syndrome
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Mismatch repair cancer syndrome (MMRCS) is a cancer syndrome associated with biallelic DNA mismatch repair mutations.[1] It is also known as Turcot syndrome (after Jacques Turcot, who described the condition in 1959) and by several other names.[1]
Quick Facts Other names, Specialty ...
Mismatch repair cancer syndrome | |
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Other names | Brain tumor-polyposis syndrome, Glioma-polyposis syndrome |
This condition is inherited in an autosomal recessive manner | |
Specialty | Oncology |
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In MMRCS, neoplasia typically occurs in both the gut and the central nervous system (CNS).[1] In the large intestine, multiple colonic polyps develop; in the CNS, brain tumors.