Monastrol
Chemical compound / From Wikipedia, the free encyclopedia
Monastrol is a cell-permeable small molecule inhibitor discovered by Thomas U. Mayer in the lab of Tim Mitchison. Monastrol was shown to inhibit the kinesin-5 (also known as KIF11, Kinesin Eg5), a motor protein important for spindle bipolarity.[1]
Quick Facts Names, Identifiers ...
Names | |
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IUPAC name
ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate | |
Other names
Monastrol | |
Identifiers | |
3D model (JSmol) |
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ChEBI | |
ChEMBL | |
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PubChem CID |
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CompTox Dashboard (EPA) |
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Properties | |
C14H16N2O3S | |
Molar mass | 292.35344 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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