Myosin-heavy-chain kinase
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In enzymology, a myosin-heavy-chain kinase (EC 2.7.11.7) is an enzyme that catalyzes the chemical reaction
- ATP + [myosin heavy-chain] ADP + [myosin heavy-chain] phosphate
Quick Facts Identifiers, EC no. ...
myosin heavy chain kinase | |||||||||
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Identifiers | |||||||||
EC no. | 2.7.11.7 | ||||||||
CAS no. | 64763-54-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are ATP and myosin heavy-chain, whereas its two products are ADP and myosin heavy-chain phosphate.
This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[myosin heavy-chain] O-phosphotransferase. Other names in common use include
- ATP:myosin-heavy-chain O-phosphotransferase
- calmodulin-dependent myosin heavy chain kinase
- MHCK
- MIHC kinase
- myosin heavy chain kinase
- myosin I heavy-chain kinase
- myosin II heavy-chain kinase
- [myosin-heavy-chain] kinase
- myosin heavy chain kinase A
- STK6.