NAD+ synthase (glutamine-hydrolysing)
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In enzymology, a NAD+ synthase (glutamine-hydrolysing) (EC 6.3.5.1) is an enzyme that catalyzes the chemical reaction
- ATP + deamido-NAD+ + L-glutamine + H2O AMP + diphosphate + NAD+ + L-glutamate. In eukaryotes, this enzyme contains a glutaminase domain related to nitrilase.[1]
Quick Facts + synthase (glutamine-hydrolyzing), Identifiers ...
NAD+ synthase (glutamine-hydrolyzing) | |||||||||
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Identifiers | |||||||||
EC no. | 6.3.5.1 | ||||||||
CAS no. | 37318-70-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The substrates of this enzyme are ATP, deamido-NAD+, L-glutamine, and H2O, whereas its 4 products are AMP, diphosphate, NAD+, and glutamate [2]
This enzyme participates in glutamate metabolism and nicotinate and nicotinamide metabolism.