the brain. Naltrexone was first made in 1965 and was approved for medical use in the United States in 1984. Naltrexone, as naltrexone/bupropion (brand name
450 mg of bupropion hydrochloride). In addition to single-drug formulations, bupropion is formulated in combinations including naltrexone/bupropion (Contrave;
aid bupropion (previously called amfebutamone), which has also been developed as a weight-loss medicine when in a combination product with naltrexone. Amfepramone