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Neo-Darwinism is generally used to describe any integration of Charles Darwin's theory of evolution by natural selection with Gregor Mendel's theory of genetics. It mostly refers to evolutionary theory from either 1895 (for the combinations of Darwin's and August Weismann's theories of evolution) or 1942 ("modern synthesis"), but it can mean any new Darwinian- and Mendelian-based theory, such as the current evolutionary theory.