Nucleoside-triphosphatase
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) is an enzyme that catalyzes the chemical reaction
- NTP + H2O NDP + phosphate
Quick Facts Identifiers, EC no. ...
nucleoside-triphosphatase | |||||||||
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Identifiers | |||||||||
EC no. | 3.6.1.15 | ||||||||
CAS no. | 9075-51-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are NTP and H2O, whereas its two products are NDP and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is unspecific diphosphate phosphohydrolase. Other names in common use include nucleoside triphosphate phosphohydrolase, nucleoside-5-triphosphate phosphohydrolase, and nucleoside 5-triphosphatase. This enzyme participates in purine metabolism and thiamine metabolism.