Obeticholic acid
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Obeticholic acid (OCA), sold under the brand name Ocaliva, is a semi-synthetic bile acid analogue which has the chemical structure 6α-ethyl-chenodeoxycholic acid. It is used as a medication used to treat primary biliary cholangitis. Intercept Pharmaceuticals Inc. hold the worldwide rights to develop OCA outside Japan and China, where it is licensed to Dainippon Sumitomo Pharma.[4]
Quick Facts Clinical data, Trade names ...
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Trade names | Ocaliva |
Other names | 6α-ethyl-chenodeoxycholic acid; INT-747 |
AHFS/Drugs.com | Monograph |
MedlinePlus | a616033 |
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Routes of administration | By mouth |
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ECHA InfoCard | 100.238.318 |
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Formula | C26H44O4 |
Molar mass | 420.634 g·mol−1 |
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Melting point | 108–110 °C (226–230 °F) [3] |
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